L-Dihydroorotic acid

CAS No. 5988-19-2

L-Dihydroorotic acid ( —— )

Catalog No. M19640 CAS No. 5988-19-2

L-Dihydroorotic acid also known as (S)-45-dihydroorotate or dihydro-L-orotate belongs to the class of organic compounds known as alpha amino acids and derivatives.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 35 In Stock
500MG 86 In Stock
1G 128 In Stock

Biological Information

  • Product Name
    L-Dihydroorotic acid
  • Note
    Research use only not for human use.
  • Brief Description
    L-Dihydroorotic acid also known as (S)-45-dihydroorotate or dihydro-L-orotate belongs to the class of organic compounds known as alpha amino acids and derivatives.
  • Description
    L-Dihydroorotic acid also known as (S)-45-dihydroorotate or dihydro-L-orotate belongs to the class of organic compounds known as alpha amino acids and derivatives. Within the cell L-dihydroorotic acid is primarily located in the cytoplasm and mitochondria. L-Dihydroorotic acid exists in all eukaryotes ranging from yeast to humans. L-Dihydroorotic acid participates in a number of enzymatic reactions. In particular L-Dihydroorotic acid can be biosynthesized from ureidosuccinic acid; which is catalyzed by the enzyme cad protein. In addition L-Dihydroorotic acid and quinone can be converted into orotic acid; which is mediated by the enzyme dihydroorotate dehydrogenase (quinone) mitochondrial. In humans L-dihydroorotic acid is involved in the pyrimidine metabolism pathway. L-Dihydroorotic acid is also involved in several metabolic disorders some of which include UMP synthase deficiency (orotic aciduria) the mngie (mitochondrial neurogastrointestinal encephalopathy) pathway Beta ureidopropionase deficiency and dihydropyrimidinase deficiency.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5988-19-2
  • Formula Weight
    158.11
  • Molecular Formula
    C5H6N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:196.1 mM
  • SMILES
    OC(=O)[C@@H]1CC(=O)NC(=O)N1
  • Chemical Name
    (S)-26-dioxohexahydropyrimidine-4-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jiang G. et al.: J. Med. Chem. 44 453 (2001)
molnova catalog
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